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1.
Arq. bras. neurocir ; 36(3): 178-184, 08/09/2017.
Article in English | LILACS | ID: biblio-911206

ABSTRACT

Schwannomas arise from the Schwann cells of the peripheral and cranial nerves. They represent 8% of the primary cerebral neoplasms. Although schwannomas usually develop in sensory nerves, most often on the vestibular and trigeminal nerves, in very rare cases they can develop in motor nerves. We reported an unusual case of a 29-year-old woman with headache, nausea, vomiting, and blurred vision ongoing for 3 years. Magnetic resonance of the brain showed a solid-cystic expanded injury, heterogeneous, with limits partially defined and epicenter on the pineal gland. The lesion presented hyposignal in T1 and isosignal in T2. An intense enhancement of the solid part was observed after contrast injection. Foci of calcification and absence of diffusion restriction were also observed. The patient underwent microneurosurgery with supracerebellar infratentorial approach in a seated position. Subtotal resection was performed with maintenance of calcified tumor tissue adhered to the right Rosenthal basal vein. In the postoperative phase, the patient remained with diplopia when looking down; however, she reported improvement of headache and nausea.


Os schwannomas surgem das células de Schwann, dos nervos periféricos e cranianos e representam 8% das neoplasias cerebrais primárias. Apesar de os schwannomas se desenvolverem comumente em nervos sensoriais, mais frequentemente no nervo vestibular e trigêmeo, em casos muito raros ele pode se desenvolver em nervos motores. Relatamos um caso raro, de uma paciente do sexo feminino, 29 anos, com quadro de cefaleia, náuseas, vômitos e turvação visual há três anos. Ressonância magnética de encéfalo demonstrou lesão expansiva sólido-cística, heterogênea, com limites parcialmente definidos e epicentro na glândula pineal. Apresentou hipossinal em T1 e isossinal em T2. Houve intenso realce da parte sólida após injeção de contraste. Foram observados focos de calcificação e ausência de restrição à difusão. A paciente foi submetida a tratamento microneurocirúrgico com acesso infratentorial supracerebelar em posição sentada. Houve ressecção subtotal com manutenção de tecido tumoral calcificado aderido a veia basal de Rosenthal direita. No pós-operatório, a paciente permaneceu com diplopia na mirada ocular para baixo, entretanto apresentou melhora de cefaleia e náuseas.


Subject(s)
Humans , Female , Adult , Trochlear Nerve , Neurilemmoma , Neurilemmoma/diagnostic imaging
2.
Rev. bras. mastologia ; 25(4): 125-130, out.-dez. 2015. tab, ilus
Article in Portuguese | LILACS-Express | LILACS | ID: lil-781045

ABSTRACT

Objetivo: Verificar a acurácia da ultrassonografia no seguimento das lesões mamárias diagnosticadas previamente como doenças benignas pela citopatologia. Métodos: Foram selecionados casos de pacientes submetidas à punção aspirativa com agulha fina de lesões mamárias e que a citopatologia descreveu achados benignos. Um grupo foi seguido com ultrassonografia e outro submetido à biópsia excisional ou incisional das lesões. A acurácia foi calculada a partir da sensibilidade, especificidade, valor preditivo positivo e negativo; e análise através da curva ROC. Resultados: Foram analisados 507 resultados citopatológicos, no período de agosto de 2002 a dezembro de 2010. Desses, 23,23% foram excluídos do estudo por terem sido classificados como material inadequado. A acurácia da punção aspirativa com agulha fina foi de 91,76%; quando comparada com os resultados anatomopatológicos. Já a acurácia da ultrassonografia foi de 99,38%. Quando comparados simultaneamente a biópsia e a ultrassonografia, utilizando a curva ROC, a acurácia do teste índice foi de 88 e 84%, respectivamente. Conclusão: O seguimento ultrassonográfico das lesões mamárias pode ser uma alternativa no seguimento de lesões mamárias diagnosticadas previamente como benignas à citopatologia.


Objective: The objective is to verify the accuracy of ultrasonography in the follow-up of breast lesions previously diagnosed as benign diseases by cytopathology. Methods: A retrospective and observational study aimed to compare the accuracy of fine needle aspiration in relation to the pathological exam and to the ultrasonography, in follow-up of breast lesions through the calculation of the sensitivity, specificity, positive predictive value, negative predictive value, and using the ROC curve. Results: 507 fine needle aspirations were analyzed in the period of August 2002 to December 2010. A total of 23.23% were excluded from the study because they were considered as inappropriate material. When compared to the pathological exam, the accuracy of fine needle aspiration was 91.76%. When related to the ultrasonography, the accuracy was 99.38%. When compared to both pathological exam and ultrasonography, using the ROC curve, the accuracy of the index test was 88 and 84%, respectively. Conclusion: The radiological follow-up of the breast lesions can be an alternative in the follow-up of lesions previously diagnosed as benign to fine needle aspiration.

3.
An. bras. dermatol ; 90(1): 27-34, Jan-Feb/2015. tab, graf
Article in English | LILACS | ID: lil-735725

ABSTRACT

BACKGROUND: Leprosy and HIV are diseases that have a major impact on public health in Brazil. Patients coinfected with both diseases, appear to be at higher risk to develop leprosy reactions. OBJECTIVE: The aim of this study is to describe the histopathological aspects of cutaneous lesions during reactional states in a group of patients with HIV-leprosy coinfection, compared to patients with leprosy, without coinfection. METHODS: Two groups were established: group 1 comprised of 40 patients coinfected with HIV-leprosy; group 2, comprised of 107 patients with leprosy only. Patients presenting reactional states of leprosy had their lesions biopsied and comparatively evaluated. RESULTS: Reversal reaction was the most frequent feature in both groups, with dermis edema as the most common histopathological finding. Giant cells were seen in all group 1 histopathological examinations. Dermis edema was the most common finding in patients with erythema nodosum leprosum. CONCLUSION: Few histopathological differences were found in both groups, with reversal reaction as the most significant one, although this fact should be analyzed considering the predominant BT clinical form in the coinfected group and BB form in the group without HIV. Larger prospective studies in patients with HIV-leprosy coinfection are needed to confirm and broaden these results. .


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , HIV Infections/pathology , Leprosy/pathology , Age Distribution , Biopsy , Chi-Square Distribution , Coinfection/pathology , Granuloma/pathology , Risk Factors , Sex Distribution , Skin/pathology
4.
Ciênc. rural ; 44(10): 1790-1796, 10/2014. graf
Article in English | LILACS | ID: lil-726299

ABSTRACT

The morphogenesis of giant missionary grass (Axonopus jesuticus x A. scoparius) was evaluated in this study in response to the application of 0, 40, 80, 120, 160, and 200m³ ha-1year-1 of pig slurry, calculated to provide 0, 100, 200, 300, 400, and 500kg N ha-1year-1, respectively. The experiment was carried out in the field, at Chapecó, Santa Catarina, Brazil, in 2010-2011. The doses were fractioned in four applications, performed after the pasture cuttings, during the growth season of the grass. Morphogenetic evaluations were performed weekly between 10/26/2010 and 12/07/2010 (spring), 12/14/2010 and 01/11/2011 (late spring/early summer), 01/18/2011 and 02/07/2011 (summer), and 02/15/2011 and 03/21/2011 (late summer). The leaf senescence, leaf elongation, and pseudoculm elongation rates, canopy and pseudoculm heights, leaf blade length, and tillering increased because of fertilization. The application of pig slurry as a source of nitrogen alters the tissue flow of giant missionary grass, which requires attention to pasture management in order to maximize the efficiency of forage use and to prevent losses of herbage by leaf senescence.


A morfogênese da grama-missioneira-gigante (Axonopus jesuticus x A. scoparius) tirar itálico dos parentes foi avaliada neste estudo em resposta à aplicação de doses de 0, 40, 80, 120, 160 e 200m³ ha-1ano-1 de dejeto líquido de suínos, calculadas para suprir 0, 100, 200, 300, 400 e 500kg de N ha-1ano-1, respectivamente. O experimento foi realizado no campo, em Chapecó, Santa Catarina, Brasil, em 2010-2011. As doses foram fracionadas em quatro aplicações, após os cortes da pastagem, durante a estação de crescimento da gramínea. As avaliações morfogenéticas ocorreram semanalmente entre 26/10/2010 e 07/12/2010 (primavera), 14/12/2010 e 11/01/2011 (final da primavera/início do verão), 18/01/2011 e 07/02/2011 (verão), e 15/02/2011 e 21/03/2011 (final do verão). As taxas de senescência foliar, alongamento foliar e alongamento do pseudocolmo, a altura do dossel e do pseudocolmo, o comprimento de lâmina foliar e o afilhamento foram incrementados como resultado da fertilização. A aplicação de dejetos de suínos como fonte de nitrogênio altera o fluxo de tecido de grama-missioneira-gigante, o que requer atenção ao manejo da pastagem para maximizar a eficiência de uso da forragem e prevenir perdas por senescência.

5.
An. bras. dermatol ; 89(2): 318-319, Mar-Apr/2014. graf
Article in English | LILACS | ID: lil-706978

ABSTRACT

Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.


Subject(s)
Humans , Female , Aged , Psoriasis/pathology , Keratosis/pathology , Skin/pathology , Biopsy , Leg Dermatoses/pathology
6.
Ciênc. rural ; 44(3): 461-466, mar. 2014. ilus
Article in Portuguese | LILACS | ID: lil-704143

ABSTRACT

Este trabalho teve como objetivo avaliar a morfogênese da grama-tapete (Axonopus affinis) adubada durante dois anos com dejeto líquido de suínos (DLS). Na média de dois anos, foram aplicados 0, 51, 102, 153, 204 e 255m³ de DLS ha-1, calculados para prover 0, 100, 200, 300, 400 e 500kg de N/ha/ano, respetivamente. A morfogênese foi avaliada na primavera e verão de 2008-2009 e 2009-2010, considerando-se como temperatura basal 10°C para cálculo da soma térmica no intervalo entre as amostragens. Houve aumento linear no número de perfilhos, taxa de alongamento de perfilhos, taxa de expansão foliar e índice de área foliar em função das doses de DLS. Não houve efeito da adubação na taxa de alongamento de pseudocolmo (0,004cm GD-1), taxa de aparecimento foliar (0,004 folha perfilho-1 GD-1) e filocrono (274GD).


This study aimed to evaluate the morphogenesis of carpet grass fertilized for two years with pig slurry (PS). On the average of two years were applied 0, 51, 102, 153, 204 and 255m³ of PS ha-1, calculated to provide 0, 100, 200, 300, 400 and 500kg of N ha-1 year-1, respectively. The morphogenesis was evaluated in the spring and summer of 2008-2009 and 2009-2010, considering 10°C as threshold temperature to evaluate the thermal sum in degree-days (DD) between the samplings. The fertilization linearly increased the tiller number, tiller elongation rate, leaf elongation rate and leaf area index. There was no effect of the fertilization on pseudoculm elongation rate (0.004cm DD-1), leaf appearance rate (0.004 leaf tiller-1 DD-1) and phyllochron (274DD).

7.
Ciênc. rural ; 44(2): 276-282, fev. 2014.
Article in English | LILACS | ID: lil-701347

ABSTRACT

This study aimed to evaluate the chemical and anatomical attributes of leaves of giant missionary grass to application of 0, 62, 124, 186, 248 and 310m³ ha-1 of pig slurry. At 83 days after the last application of fertilizer, the leaf blades were collected, fixed in FAA 70%, sectioned, stained, photographed and digitalized. The transversal section of leaf blades were evaluated for proportion of epidermis, lignified vascular tissue + sclerenchyma, non-lignified vascular tissue and parenchyma with an image-processing system calibrated to 1mm pixel-1. Leaf samples were analyzed for crude protein, acid detergent fiber, neutral detergent fiber and hemicellulose content by near infrared reflectance spectroscopy. The pig slurry application up to 310m³ ha-1 significantly increased the percentage of crude protein, parenchyma, epidermis, non-lignified vascular tissue and hemicellulose, while decreasing the percentage of acid detergent fiber and lignified vascular tissue + sclerenchyma. The Pearson's correlation was positive between crude protein and non-lignified vascular tissue, and between acid detergent fiber and lignified vascular tissue + sclerenchyma. The percentage of hemicellulose was positively correlated with epidermis, parenchyma and non-lignified vascular tissue. A negative correlation between acid detergent fiber and epidermis, parenchyma and non-lignified vascular tissue was observed.


Este trabalho teve como objetivo avaliar os atributos anatômicos e químicos da grama-missioneira-gigante à aplicação de 0, 62, 124, 186, 248 and 310m³ ha-1. Decorridos 83 dias do último corte e da aplicação do dejeto, as lâminas foliares foram coletadas, fixadas em FAA 70%, seccionadas, coradas, fotografadas e digitalizadas. Secções transversais das lâminas foliares foram avaliadas quanto à proporção das áreas de epiderme, tecido vascular lignificado + esclerênquima, tecido vascular não lignificado e parênquima, na região entre a quilha e o segundo maior feixe vascular, com sistema de processamento de imagem calibrado para 1mm pixel-1. Amostras de folhas foram coletadas e analisadas quanto ao teor de proteína bruta, fibra insolúvel em detergente ácido e fibra insolúvel em detergente neutro, pelo método de espectrometria de reflectância no infravermelho proximal. A aplicação de até 310m³ ha-1 do dejeto líquido de suíno aumentou os percentuais de proteína bruta, hemicelulose, parênquima e tecido vascular não lignificado, reduzindo os percentuais de fibra insolúvel em detergente ácido e tecido vascular lignificado + esclerênquima. A correlação de Pearson foi positiva entre o percentual de proteína bruta e tecido vascular não lignificado, e entre o percentual de fibra insolúvel em detergente ácido e tecido vascular lignificado + esclerênquima. O percentual de hemicelulose mostrou correlação positiva com epiderme, parênquima e tecido vascular não lignificado. Houve correlação negativa entre o percentual de fibra insolúvel em detergente ácido e epiderme, parênquima e tecido vascular não lignificado. O dejeto líquido de suínos, utilizado como fonte de nitrogênio, promove melhoria em atributos químicos e anatômicos, que afetam o valor nutritivo da grama-missioneira-gigante.

8.
An. bras. dermatol ; 88(6): 994-995, Nov-Dec/2013. graf
Article in English | LILACS | ID: lil-699003

ABSTRACT

Paracoccidioidomycosis presenting as a sarcoid-like plaque may be misdiagnosed as leprosy, especially when shared endemic areas are concerned. We report the case of a Brazilian male patient presenting with an ulcerated plaque on his left ear and neighboring areas. The plaque simulated tuberculoid leprosy type 1 reaction, both clinically and histopathologically. A perineural granuloma with no organisms detected by routine and Fite-Faraco staining reinforced that diagnosis. Paracoccidioidomycosis was confirmed only after a second biopsy, taken from the ulcerated area.


Paracoccidioidomicose expressando-se como placa sarcoídica pode ser confundida com hanseníase, especialmente em zonas endêmicas comuns às duas condições. Apresentamos um paciente brasileiro, com placa ulcerada na orelha direita e em áreas vizinhas que simulava, clinica e histopatologicamente, hanseníase tuberculoide em reação tipo 1. O encontro de granuloma perineural, sem parasitas detectáveis às colorações de rotina e Fite-Faraco, reforçou a hipótese de hanseníase. Apenas com uma nova biópsia, desta vez da área ulcerada, a paracoccidioidomicose pôde ser confirmada.


Subject(s)
Humans , Male , Middle Aged , Ear Diseases/pathology , Granuloma/pathology , Paracoccidioidomycosis/pathology , Biopsy , Diagnosis, Differential , Ear, External/pathology , Leprosy, Tuberculoid/pathology
9.
An. bras. dermatol ; 88(6,supl.1): 113-115, Nov-Dec/2013. graf
Article in English | LILACS | ID: lil-696790

ABSTRACT

Tufted angioma is an acquired vascular proliferation with specific histological characteristics. The most common clinical features are erythematous macules. It occurs predominantly in children and young adults, especially in the chest and neck. We report the case of a male patient, 12 years old, with an increased right ear auricle associated with erythematous macules and increased local temperature, referred with a diagnosis of lepromatous leprosy; however, this diagnosis was questioned. Histopathology was consistent with tufted angioma.


O Hemangioma em penacho é uma proliferação vascular adquirida de características histológicas peculiares. Sua característica clínica mais comum são máculas eritematosas. Ocorre predominantemente em crianças e adultos jovens, principalmente no tórax e pescoço. Relata-se o caso de paciente do sexo masculino, 12 anos, com aumento do pavilhão auricular direito associado a máculas eritematosas e aumento da temperatura local, encaminhado com diagnóstico de Hanseníase Virchowiana, entretanto, tal diagnóstico foi questionado. Histopatologia compatível com Hemangioma em penacho.


Subject(s)
Child , Humans , Male , Ear Auricle/pathology , Ear Neoplasms/pathology , Hemangioma/pathology , Skin Neoplasms/pathology , Biopsy , Diagnosis, Differential , Leprosy, Lepromatous/pathology
10.
An. bras. dermatol ; 88(6): 1005-1007, Nov-Dec/2013. graf
Article in English | LILACS | ID: lil-699011

ABSTRACT

Granular cell tumor is a rare benign neoplasm of neural origin. We report the case of a female patient, 27 years old presenting a brown-red nodule in the right arm, which pathological examination showed to be formed by polygonal cells with eosinophilic granular cytoplasm and immunohistochemistry positive for S100 protein and CD68. Granular cell tumor is usually solitary and in half the cases located in the head and neck areas, 30% of these in the tongue. It is most frequent between the third and fifth decades of life in women and people of African-American ethnicity. Its origination is controversial, including the possible origins in muscle, fibroblasts, neural crest, neural sheath or histiocytes. The positivity for S-100 and CD68 suggest the neural origin.


O tumor de células granulares é uma neoplasia benigna rara, de origem neural. Relatamos caso de paciente feminina, 27 anos, com nódulo de superfície acastanhada no braço direito, cujo exame anatomopatológico evidenciou densa proliferação de células, com amplo citoplasma contendo grânulos eosinofílicos, e imuno-histoquímica positiva para proteínas S100 e CD68. O tumor de células granulares é geralmente solitário e, em metade dos casos, localiza-se em cabeça e pescoço, dos quais 23% na língua. É mais frequente entre a terceira e a quinta décadas de vida, em mulheres e pessoas de etnia negra. A positividade para S-100 e CD68 favorece origem neural.


Subject(s)
Humans , Female , Adult , Skin Neoplasms/pathology , Granular Cell Tumor/pathology , Immunohistochemistry , Antigens, Differentiation, Myelomonocytic/metabolism , S100 Proteins/metabolism , Biomarkers, Tumor/metabolism , Antigens, CD/metabolism
11.
An. bras. dermatol ; 88(4): 614-616, ago. 2013. graf
Article in English | LILACS | ID: lil-686533

ABSTRACT

Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was performed and the histopathological evaluation was consistent with dermatofibroma. Only three cases of dermatofibroma associated with tatooing were reported in litetature. We report an additional case and review the literature regarding cutaneous reactions to tattoos.


Tatuagens têm sido associadas com uma variedade de complicações incluindo reações inflamatórias e granulomatosas, transmissão de infecções e neoplasias. Relatamos um caso de homem com 24 anos de idade que apresentava há dois meses nódulo eritematoso sob pigmento preto de uma tatuagem na coxa direita. A biópsia excisional foi realizada e a avaliação histológica foi consistente com dermatofibroma. Apenas três casos da associação dermatofibroma e tatuagem foram relatados na literatura. Nós reportamos um caso adicional e revisamos a literatura sobre reações cutâneas em tatuagens.


Subject(s)
Humans , Male , Young Adult , Histiocytoma, Benign Fibrous/etiology , Skin Neoplasms/etiology , Tattooing/adverse effects , Biopsy , Histiocytoma, Benign Fibrous/pathology , Skin Neoplasms/pathology
12.
An. bras. dermatol ; 88(1): 84-89, fev. 2013. graf
Article in English | LILACS | ID: lil-667940

ABSTRACT

Clear cell acanthoma or Degos' acanthoma is a distinct disease concerning its clinical, histopathological, and immunohistochemical features. Its pathologic nature - whether neoplastic or reactive - is still under dispute among researchers. The disease shows a chronic course and often presents with a single papulonodular lesion on the lower limbs of adults. However, cases with multiple lesions, sometimes occurring in an eruptive fashion, and with clear variation in the size and shape of the cutaneous lesions have been reported. So far, five cases in which the lesions were exclusively located in the nipple area have been reported, all in Korean women. Four of these cases mimicked eczema and one, a polypoid nodule. The aim of this article is to present clinical, histopathological, and immunohistochemical features of two additional cases in Brazilian women with similar nipple topography.


O acantoma de células claras ou acantoma de Degos é uma doença bem individualizada quanto aos seus aspectos clínicos, histopatológicos e imuno-histoquímicos. Sua natureza patológica - se neoplásica ou reativa - ainda é debatida por pesquisadores. De evolução crônica, ocorre predominantemente nos membros inferiores de adultos, em geral como lesão papulonodular única. Entretanto, foram observados casos com lesões múltiplas, por vezes de caráter eruptivo, e com notável variação de tamanho e forma das eflorescências cutâneas. Há relatos de cinco casos com localização exclusiva na aréola e no mamilo, quatro simulando eczema e um como nódulo polipoide; todos ocorridos em mulheres coreanas. O objetivo deste trabalho é apresentar os aspectos clínicos, histopatológicos e imuno-histoquímicos de dois novos casos da doença, com idêntica topografia areolomamilar, observados em mulheres brasileiras.


Subject(s)
Adolescent , Adult , Female , Humans , Acanthoma/pathology , Nipples/pathology , Skin Neoplasms/pathology , Brazil , Diagnosis, Differential , Immunohistochemistry
13.
An. bras. dermatol ; 86(4,supl.1): 69-71, jul,-ago. 2011. ilus
Article in Portuguese | LILACS | ID: lil-604124

ABSTRACT

O granuloma anular elastolítico gigantocelular é dermatose granulomatosa rara, caracterizada, histologicamente, por fagocitose das fibras elásticas por células gigantes multinucleadas e, clinicamente, por placas anulares com bordas elevadas e centro atrófico, com preferência por áreas expostas. A patogênese é controversa. Descreve-se um caso de mulher de 44 anos, com achados clínicos e histológicos clássicos, que apresentou boa resposta à hidroxicloroquina, após o período de 1 mês.


Annular elastolytic giant cell granuloma is a rare granulomatous skin disease characterized histologically by phagocytosis of elastic fibers by multinucleated giant cells and clinically by annular patches with elevated borders and atrophic centers found mainly on sun-exposed skin. The pathogenesis of the disease is controversial. We report the case of a 44-year-old woman with classical clinical and histological findings of the disease whose condition improved when hydroxychloroquine was administered over a four-week period.


Subject(s)
Adult , Female , Humans , Granuloma, Giant Cell/pathology , Skin Diseases/pathology , Antirheumatic Agents/therapeutic use , Elastic Tissue/pathology , Forearm , Granuloma, Giant Cell/drug therapy , Hydroxychloroquine/therapeutic use , Skin Diseases/drug therapy
14.
An. bras. dermatol ; 86(4,supl.1): 82-84, jul,-ago. 2011. ilus
Article in Portuguese | LILACS | ID: lil-604128

ABSTRACT

O líquen escleroso e atrófico é uma doença crônica da pele e mucosas, que, usualmente, afeta a área genital de mulheres. Poucos casos de líquen escleroso e atrófico, confinados nos pés e/ou mãos, têm sido relatados. Relatamos um caso de líquen escleroso e atrófico envolvendo as extremidades e,posteriormente, a área perigenital.


Lichen sclerosus et atrophicus is a chronic disorder of the skin and mucosal surfaces, most commonly affecting the female genitalia. Few cases of lichen sclerosus et atrophicus confined to the feet and/or hands have been reported. We report a case of lichen sclerosus et atrophicus involving first the extremities and then the perigenital area.


Subject(s)
Female , Humans , Middle Aged , Foot Dermatoses/diagnosis , Foot Dermatoses/pathology , Lichen Sclerosus et Atrophicus/pathology , Anti-Inflammatory Agents/therapeutic use , Chronic Disease , Clobetasol/therapeutic use , Foot Dermatoses/drug therapy , Immunosuppressive Agents/therapeutic use , Lichen Sclerosus et Atrophicus/drug therapy , Tacrolimus/therapeutic use , Vulvar Diseases/drug therapy , Vulvar Diseases/pathology
15.
An. bras. dermatol ; 86(4,supl.1): 190-192, jul,-ago. 2011. ilus
Article in Portuguese | LILACS | ID: lil-604156

ABSTRACT

Tumor triquilemal proliferante é uma neoplasia incomum que surge do istmo folicular, cuja característica histológica é a presença de ceratinização triquilemal. Apresenta-se usualmente como nódulo solitário no couro cabeludo de mulheres idosas. Descreve-se um caso de tumor triquilemal proliferante que se apresenta como lesão tumoral nodular na região glútea de uma jovem de 16 anos de idade.


Proliferating trichilemmal tumor (PTT) is an uncommon neoplasm arising from the follicular isthmus. Its histological characteristic is the presence of trichilemmal keratinization. PTT usually presents as a solitary nodule on the scalp of elderly women. We describe a case of a PTT on the gluteal region (buttocks) of a 16-year-old female, presenting as a solitary nodule.


Subject(s)
Adolescent , Female , Humans , Epidermal Cyst/pathology , Skin Neoplasms/pathology , Buttocks/pathology , Epidermal Cyst/surgery , Skin Neoplasms/surgery
16.
An. bras. dermatol ; 86(2): 373-374, mar.-abr. 2011. ilus
Article in Portuguese | LILACS | ID: lil-587681

ABSTRACT

Doença de Jorge Lobo (DJL) é infecção granulomatosa cutânea crônica produzida pelo fungo Lacazia loboi, cujas lesões mais típicas têm aspecto queloidiano, com localizações preferenciais em membros e orelhas. As lesões restringem-se à pele, havendo apenas uma referência, do conhecimento dos autores, à localização em semimucosa labial. Apresenta-se caso de doença de Jorge Lobo em paciente masculino, com lesão papulonodular no vermelhão do lábio superior, à esquerda, de dez anos de evolução, exitosamente submetida a tratamento cirúrgico, sem recidiva após oito anos.


Jorge Lobo's Disease (JLD) is a chronic granulomatous cutaneous mycosis caused by Lacazia loboi. The most typical lesions are keloid-like growths preferentially located on limbs and ears. To the best of the authors' knowledge, only one labial case has previously been reported. We describe the case of a man who presented with a left-sided papulonodular lesion of 10 years' duration on the vermillion border of the upper lip. A successful surgical resection of the lesion was performed and there was no recurrence in eight years of follow-up.


Subject(s)
Humans , Male , Middle Aged , Lip Diseases/microbiology , Lobomycosis/pathology , Follow-Up Studies , Lip Diseases/pathology , Lip Diseases/surgery , Lobomycosis/surgery
17.
Rev. para. med ; 24(3/4)jul.-dez. 2010. ilus
Article in Portuguese | LILACS-Express | LILACS | ID: lil-603877

ABSTRACT

Relatar dificuldades diagnósticas face à ocorrência simultânea, num mesmo paciente,de duas enfermidades infecciosas com aspectos clínicos semelhantes. Relato de caso: homemde 21 anos, há nove meses apresentando placas eritematovioláceas infiltradas na face, dorso e pédireito. A histopatologia de uma lesão do dorso evidenciou quadro de dermatite granulomatosa,com pesquisa de bacilos álcool-ácido resistentes negativa à coloração de Fite-Faraco. Umdiagnóstico de hanseníase dimorfo-tuberculoide foi realizado e o paciente submetido àpoliquimioterapia multibacilar. As lesões do pé direito evoluíram com ulceração e pesquisadireta positiva para formas amastigotas de Leishmania spp; entretanto, um exame imunohistoquímicodo material emblocado da biópsia anterior, do dorso, mostrou resultado negativocom anticorpo antileishmania, Considerações finais: A conclusão diagnóstica de coinfecçãohanseníase-leishmaniose tegumentar para o caso apresentado, somente foi possível graças àcorrelação clínico-patológica e realização de provas histoquímicas e imuno-histoquímicas.


To report diagnostic difficulties that may arise when a simultaneous occurrence oftwo infectious diseases presenting similar clinical features takes place in a single patient. Casereport: a 21-year-old male presented with violaceous, infiltrated plaques on his face, dorsumand right foot. A granulomatous dermatitis was diagnosed histologically in a biopsy taken fromthe dorsum, with no demonstrable acid-fast organisms on Fite-Faraco stain. A diagnosis ofbordeline-tuberculoid leprosy was concluded, and the patient was given multibacillarypolychemotherapy. The lesions on the right foot became ulcerated, and positive smears forLeishmania spp amastigotes were obtained. However, immunohistochemistry failed todemonstrate leishmania antigens in recuts of the paraffin-embedded material from the originaldorsal biopsy. Final considerations: the diagnosis of leprosy-leishmaniasis coinfection to thiscase has been possible only after clinical-pathological correlation as well as histochemical andimmunohistochemical procedures were carried out

18.
An. bras. dermatol ; 85(4): 512-515, jul.-ago. 2010. ilus
Article in Portuguese | LILACS | ID: lil-560581

ABSTRACT

Biópsias são ocasionalmente necessárias para confirmação diagnóstica de sífilis secundária, normalmente obtida por correlação clínico-sorológica. Entretanto, o exame histopatológico pode oferecer pistas que conduzam a um diagnóstico em casos antes insuspeitos ou de apresentação clínica incomum. Apresentamos um paciente de 35 anos, há dois com lesões acrômicas vitiligoides, para o qual sífilis foi sugerida somente após o exame histopatológico. Alguns aspectos microscópicos observados são discutidos e comparados com dados disponíveis na literatura.


Biopsies are occasionally necessary to confirm the diagnosis of secondary-stage syphilis, currently achieved by clinico-serological correlation. However, histopathologic examination may offer clues that can lead to the diagnosis of the disease in previously unsuspected or unusual cases. We report the case of a 35-year-old male patient with vitiligo-like lesions for two years, whose diagnosis of syphilis was suggested only after histopathologic examination. Some microscopic aspects observed are discussed and compared to data from the literature.


Subject(s)
Adult , Humans , Male , Hypopigmentation/pathology , Syphilis, Cutaneous/pathology , Vitiligo/pathology , Biopsy , Diagnosis, Differential , Hypopigmentation/etiology , Syphilis, Cutaneous/complications
19.
Arch. méd. Camaguey ; 14(3)mayo-jun. 2010. tab
Article in Spanish | LILACS | ID: lil-577909

ABSTRACT

Fundamento: la lactancia materna constituye el alimento natural de la especie humana, por ello debemos agotar todos nuestros esfuerzos en garantizar que el niño sea alimentado exclusivamente a pecho al menos hasta los primeros seis meses después de nacido. Objetivo: demostrar la eficacia de un programa sobre lactancia materna en un grupo de madres. Método: se realizó un estudio de intervención educativa para demostrar la eficacia de un programa sobre lactancia materna en un grupo de madres de diez consultorios del Policlínico Este, Municipio Camagüey desde enero de 2007 a mayo de 2008. Constituyeron el universo cincuenta y cinco madres con fechas probables de parto entre el primero de junio y el treinta y uno de agosto de 2007, a las que se les aplicó un formulario con diferentes variables y una encuesta de conocimientos antes y después de la intervención. Resultados: predominó el grupo de treinta a treinta y cuatro años. El 83,3 por ciento de las encuestadas no conocían adecuadamente de lactancia materna, y sólo el 9,72 por ciento la alcanzó en forma exclusiva hasta más de seis meses. Conclusiones: los niños que no recibieron lactancia materna exclusiva hasta el sexto mes se enfermaron con mayor frecuencia, la intervención resultó satisfactoria pues se elevó el nivel de conocimientos de las participantes y se logró que un mayor número de mujeres lactara hasta después del sexto mes.


Background: breast-feeding constitutes the natural food of human species, that is why we should exhaust all our efforts in guaranteeing the boy is exclusively fed at least to breast until the first six months after born. Objective: to demonstrate the effectiveness of a breast-feeding program in a group of mothers. Method: an educational intervention study to demonstrate the effectiveness of a breast-feeding program in a group of mothers of ten doctor's offices of the East Polyclinic, Camagüey Municipality was performed from January 2007 to May 2008. The universe was constituted by 55 mothers with probable childbirth dates among June 1st and August 31 2007, to those were applied a form with different variables and a knowledge survey before and after the intervention. Results: the group from 30 to 34 years prevailed. The 83,3 percent of those interviewed didn't know appropriately of breast-feeding, and 9,72 percent only reached it in exclusive way until more than six months. Conclusions: children didn't receive exclusive breast-feeding until the sixth month got sick with more frequency, the intervention was satisfactory because the level of the participants' knowledge rose and it was achieved a bigger number of women suckled until after the sixth month.


Subject(s)
Humans , Infant, Newborn , Infant , Breast Feeding , Population Education
20.
Arch. méd. Camaguey ; 14(3)mayo-jun. 2010. tab
Article in Spanish | LILACS | ID: lil-577914

ABSTRACT

Fundamento: el embarazo en la adolescencia es un problema a nivel mundial, se ha convertido en seria preocupación por la mayor incidencia de resultados desfavorables o por las complicaciones que puede tener para la madre y el feto. Objetivo: caracterizar socialmente a las embarazadas adolescentes del Área de Salud Integral Comunitaria El Gaitero, Maracaibo, Venezuela. Método: se realizó un estudio transversal y descriptivo embarazadas adolescentes del Área de Salud Integral Comunitaria El Gaitero, de la Parroquia Luís Hurtado Higueras, Municipio Maracaibo, Estado Zulia, Venezuela, desde enero a septiembre de 2006. El universo se constituyó por en sesenta y una embarazadas pertenecientes a los catorce consultorios de Barrio Adentro que tiene esta ASIC, en edades comprendidas entre diez y diez y ocho años, se conformó la muestra de cincuenta y dos pacientes después de aplicados los criterios de inclusión, exclusión y salida. Resultados: predominó el grupo de quince a diez y ocho años, mas de la mitad satisfacían de forma regular sus necesidades básicas. Conclusiones: las embarazadas en su mayoría no tienen cubiertas sus necesidades básicas y asumen las relaciones sexuales precoces. Entre las situaciones sociales tuvieron mayor influencia las nuevas exigencias económicas y la privación de las actividades propias de su edad.


Background: pregnancy in the adolescence is a problem at world level, it has become a serious concern because of the biggest incidence of unfavorable results or the complications that may have for mother and fetus. Objective: to characterize socially pregnant adolescents of the Community Integral Health Area El Gaitero, Maracaibo, Venezuela. Method: a cross-sectional and descriptive study to pregnant adolescents of the Community Integral Health Area El Gaitero, of the Parish Luís Hurtado Higueras, Maracaibo Municipality, Zulia State, Venezuela was performed, from January to September 2006. The universe was constituted by sixty-one pregnant adolescents belonging to fourteen consulting rooms of Barrio Adentro that has this Community Integral Health Area, in ages between ten and eighteen years, the sample was conformed by fifty-two patients after having applied the inclusion, exclusion and outlet criteria. Results: the group from fifteen to eighteen years prevailed, more than the half satisfied in a regular way their basic necessities. Conclusions: pregnant ones in its majority do not have covered their basic necessities and they assume precocious sexual intercourses. Among the social situations had bigger influence the new economic demands and the privation of the activities characteristic of their age.


Subject(s)
Humans , Female , Pregnancy , Adolescent , Pregnancy in Adolescence/psychology , Needs Assessment , Psychosocial Deprivation , Cross-Sectional Studies , Epidemiology, Descriptive , Venezuela
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